Changes and significance of auditory hallucinations score and serum BDNF levels of refractory auditory hallucinations patients after rTMS therapy
- VernacularTitle:难治性幻听患者应用rTMS治疗后幻听评分及血清BDNF水平的变化及意义
- Author:
Yunhai TAO
1
Author Information
1. 杭州市第七人民医院神经科
- Keywords:
Refractory auditory hallucinations;
rTMS;
Auditory hallucinations score;
Serum BDNF levels
- From:
China Modern Doctor
2014;(29):28-30,34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes and significance of auditory hallucinations score and serum BDNF levels of refractory auditory hallucinations patients after rTMS therapy. Methods Fifty cases of patients with refractory auditory hallucinations who were treated in our hospital from 2011 to 2013 were selected. These patients were divided into observation group and control group according to a random number table, 25 cases in each group. The patients in control group were given pseudo-rTMS stimulation therapy, while the observation group were given true rTMS stimula-tion therapy, then the auditory hallucinations score, serum BDNF levels of the two groups of patients were analyzed. Results After treatment, the auditory hallucinations score of the observation group was significantly lower (P<0.05); the serum BDNF levels after 2,4 weeks treatment of the observation group were significantly higher than those of the control group (P<0.05). Conclusion True rTMS stimulation therapy is more effective to enhance patient's BDNF lev-els, thereby greatly improve the auditory hallucinations than pseudo-rTMS stimulation therapy in the treatment of re-fractory auditory hallucinations patients.
