Therapeutic effect of mannatide injection and nedaplatin on malignant pleural effusion
- VernacularTitle:甘露聚糖肽联合奈达铂治疗恶性胸腔积液疗效观察
- Author:
Songlin HE
1
;
Hui LIU
;
Zeliang ZHAO
;
Xiao LI
Author Information
1. 川北医学院附属医院胸心外科
- Keywords:
Mannatide Injection;
Nedaplatin;
Malignant pleural effusion
- From:
China Modern Doctor
2014;(29):16-18
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of mannatide injection and nedaplatin injected in thoracic cavity in the treatment of malignant pleural effusion. Methods Ninety-four patients with malignant pleural effusion were randomly divided into two groups. The observation group of 48 patients were given mannatide injection and nedaplatin,and con-trol group of 46 patients were given only nedaplatin. Effectiveness and adverse reactions were observed after treatment. Results The effective rate was 85.4% in observation group, hihger than that in control group (69.6%)(P<0.05); The incidence rates of gastrointestinal tract and bone marrow and chest pain of observation group were 35.4%,22.9% and 18.8%. Compared with control group, the incidence of observation group had significantly lowered. There were signifi-cant differences between the two groups(P<0.05). Conclusion Mannatide injection combined with nedaplatin is more efficient and less adverse reaction for malignant pleural effusion, so it is worth popularizing.
