Diagnostic value of serum HCY level in patients with unstable angina pec-toris
- VernacularTitle:同型半胱氨酸在不稳定性心绞痛患者中的诊断价值研究
- Author:
Guanting LU
1
;
Lijian SHENG
;
Ping LI
;
Rugen WAN
Author Information
1. 浙江省金华市中心医院药剂科
- Keywords:
Homocysteine;
Unstable angina pectoris;
Diagnostic value
- From:
China Modern Doctor
2014;(29):7-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of the level of serum HCY in patients with unstable angina pectoris(UAP). Methods A total of 44 UAP patients were selected in our hospital, 53 patients with AMI and 50 healthy people were selected as control group. 2 mL vein blood was collected and the serum level of HCY was measured. Diagnostic accuracies of HCY was evaluated by receiver operating characteristic (ROC)curve analysis. Results The level of HCY [(16.33±2.06)μmol/L] in UAP group was higher than HCY [(10.43±2.32)μmol/L] in the healthy control group, lower than AMI group [(18.52±3.29)μmol/L], and the differences were statistically significant(P<0.05).Using a cut-off value of 12.26 μmol/L,HCY had the sensitivity of 72.1%,specificity of 76.0%. Conclusion The sensitivity and specificity of HCY on the early diagnosis of UAP was well, which could be a useful predictor for UAP and is worthy of clinical appli-cation.
