Application of the NT-proBNP and Hcy joint detection in the diagnosis and treatment of depression in the elderly patients with chronic heart fail-ure
- VernacularTitle:NT-proBNP及Hcy联合检测在老年抑郁症合并慢性心衰患者诊治中的应用价值
- Author:
Hongfen NI
1
;
Xiaoyan HUANG
;
Lijun CUI
;
Yuehong WU
;
Ye SHEN
Author Information
1. 浙江省湖州市第三人民医院检验科
- Keywords:
Depression;
Chronic heart failure;
N-terminal-pro-B-type natriuretic peptide;
Homocysteine
- From:
China Modern Doctor
2014;(27):54-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and diagnostic value of NT-proBNP and homocysteine (Hcy) levels in the serum of elderly depression with chronic heart failure. Methods The clinical diagnosis of depression in the elderly patients with chronic heart failure (NYHAⅠ-Ⅳ grade)80 cases (group A)and 50 cases of healthy subjects(group B), NT-proBNP and Hcy levels were detected. Well which were detected in group A,comparative analysis of results before and after conventional therapy. Results The levels of NT-proBNP(u=9.55) and Hcy (u=9.24) was significantly higher in group A than those in group B, the difference was statistically significant (P<0.01). And the levels of NT-proBNP (u=4.83)and Hcy (u=7.65)were significantly lower in group A after treatment than those of before treatment,the difference was statistically significant(P<0.01). Conclusion NT-proBNP and Hcy joint detection can help diagnose depression in the elderly patients with chronic heart failure,and as a short-term effect evaluation.
