Therapy of perioperative coagulation factor replacement in patients hav-ing fracture with hemophilia
- VernacularTitle:血友病合并骨折围手术期凝血因子替代治疗
- Author:
Song GAO
1
;
Jianping LUO
;
Chu'nan ZHONG
;
Shujian TIAN
Author Information
1. 河南省人民医院
- Keywords:
Hemophilia;
Fracture;
Coagulation factor;
Replacement treatment
- From:
China Modern Doctor
2014;(26):153-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the method and safety of coagulation factor replacement in patients having fracture with hemophilia. Methods Five male hemophilia patients with fractures were treated, and the mean follow-up period was 9 months. Under the cooperation with the hematology department. Monitored levels of factors Ⅷ and Ⅸ perioperatively, and established routine process of factor replacement, according to the China guideline of Hemophilia dialogue and tre atme nt. Results Hemophilic patients who had undergone therapy of perioperative coagulation factor replacement could suffer treatment of fractures. All patients had no complications such as hematoma, infection. But one patient firstly accepted operation, after 4months, the plate was broken, proformed conservative treatment. Conclusion Coagulation factor replacement and monitoring of coagulation factor levels are the key to the success of treament in hemophilic fracture patients.
