The effects of comprehensive health education for glutathione combined with metformin in treatment of nonalcoholic fatty liver
- VernacularTitle:综合性健康教育对还原型谷胱甘肽联合二甲双胍治疗非酒精性脂肪肝疗效的影响
- Author:
Xiaoxiao CHENG
1
;
Sujuan LU
;
Min LIN
;
Zaisheng ZHU
Author Information
1. 温州医科大学附属第一医院干部保健科
- Keywords:
Non-alcoholic fatty liver;
Metformin;
Comprehensive health education
- From:
China Modern Doctor
2014;(26):118-120,124
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of comprehensive health education for glutathione combined with met-formin in treatment of nonalcoholic fatty liver. Methods A total of 64 patients with nonalcoholic fatty liver from Jan-uary 2012 to January 2014 in our hospital, two groups were treated glutathione tablets, one tablet each time, 3 times every day; metformin tablets, one tablet each time, 3 times every day. The total courses were six months. All patients were randomly divided into intervention group and control group, the control group took random symptomatic care, the intervention group implemented a comprehensive health education interventions, the efficacy and the two groups of pa-tients after treatment ALT,AST, TC, TG, BMI levels, and BMI> 23kg/m2 abnormal rate, the rate of abnormal waist cir-cumference ≥80 cm, dyslipidemia, abnormal liver function rate, rate of abnormal ultrasound findings were compared between two groups. Results After treatment, the effective rate of the intervention group was 93.8%, was significantly higher than the control group 71.9%, the difference was statistically significant (P <0.05). After treatment, the ALT, AST, TC, TG, BMI levels of the intervention group were significantly lower than before treatment, and the ALT, AST, TC, TG, BMI of intervention group was significantly lower than the control group (P<0.05). BMI>23 kg/m2 abnormal rate, waist circumference≥80 cm abnormal rate, dyslipidemia, abnormal liver function rate, abnormal ultrasound results of intervention group were significantly lower than the control group,the difference was significant(P<0.05). Conclusion The comprehensive sexual health education can improve the effect of glutathione combined with metformin therapy in patients with non-alcoholic fatty liver, improve clinical symptoms, reduce blood fat and improve liver function, worthy of promotion and application.
