The relationship of course and recurrence after norms antiviral treatment for patients with chronic hepatitis B
- VernacularTitle:慢性乙型肝炎抗病毒治疗疗程与复发的相关性研究
- Author:
Yichu DENG
1
;
Meixiang LI
;
Wen BAO
;
Juanjuan LIU
;
Yunfeng LUO
Author Information
1. 江西省赣县人民医院内三科
- Keywords:
Chronic hepatitis B;
Nucleoside(acid)drugs;
Antiretroviral therapy;
Withdrawal relapse
- From:
China Modern Doctor
2014;(25):117-118,121
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of course and recurrence after norms antiviral treatment for patients with chronic hepatitis B. Methods All cases were confirmed by standard use of nucleos drug treatment,after treatment,followed up for 104 weeks; patients after stopping the treatment and contiued to conslidate 1 year, set the control group,patients after stopping the treatment and tiued to consolidate 3 years, as observation group,the recurrence rates and recurrence time were compared. Results The relapse rate of observation group was significantly lower than the control group(χ2=3.877,P<0.05). Control group of 38 cases,31 cases of recurrence after treatment,included 2 cases of recurrence within 2 weeks,25 cases of recurrence within 24 weeks; 4 cases relapsed after 24 weeks.Observation group of 30 cases,18 cases of relapse after discontinuation,1 case relapsed in two weeks,15 cases of recurrence within 24 weeks,2 cases relapsed after treatment 24 weeks. Conclusion The prolonged antiviral therapy can reduce the recur-rence rate of the time,but did not extend the time to recurrence,we recommend patients with chronic hepatitis B nu-cleoside (acid) drug treatment medication should be strictly in accordance with the relevant guidelines,emphasizing long-term medication to maintain efficacy,And standardize management with antiviral treatment.
