Clinical study on sufentanil infusion before extubation for supressing coughing
- VernacularTitle:静脉输注舒芬太尼抑制气管拔管时咳嗽反应的临床研究
- Author:
Yanping QIN
1
;
Kanghua ZHOU
;
Yingchun WEN
Author Information
1. 重庆市万州区人民医院麻醉科
- Keywords:
Anesthesia recovery;
Complications;
Sufentanil
- From:
China Modern Doctor
2014;(25):60-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate whether sufentanil infusion during emergence anesthesia has a effect of coughing on extubation. Methods Eighty-one patients were randomly divided into three groups. before extubation, sufentanil was administered at the group S1 at a rate of 0.2μg/(kg·h)or 0.3μg/(kg·h)at the group S2, and saline was administered to the group C. Cough score, MAP, HR and recovery profiles were recorded. The pain score, the total volume of admin-istered patient-controlled analgesia(PCA), and the postoperative nausea and vomiting(PONV) score were evaluated at 1, 6, and 24 hours after surgery. Results Compared to Group C ,Groups S1 and S2 showed significantly lower cough scores and MAP, HR on extubation. Recovery profiles showed no significant differences among the three groups. Pain score, PONV at 1 hour postoperatively, and the total volume of PCA administered at all evaluation times were signifi-cantly lower in the groups S1 and S2 than in the group C. Conclusion A sufentanil infusion(0.2~0.3)μg/(kg·h) dur-ing emergence anesthesia may suppress coughing on extubation without delaying extubation time. It may also reduce the postoperative analgesic requirement without increasing PONV.
