Influence of combined anesthesia of propofol and fentanyl or remifentanil on revival time and cognitive function of senile patients treated with gen-eral anesthesia
- VernacularTitle:丙泊酚与芬太尼或瑞芬太尼复合麻醉对老年全身麻醉后苏醒时间及认知功能的影响
- Author:
Mengli ZHU
1
Author Information
1. 浙江省永康市第一人民医院麻醉科
- Keywords:
Propofol;
Fentanyl;
Remifentanil;
Senile;
Revival;
Cognitive function
- From:
China Modern Doctor
2014;(25):57-59,63
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss influence of combined anesthesia of propofol and fentanyl or remifentanil on revival time and cognitive function of senile patients treated with general anesthesia. Methods A total of 72 cases of senile patients were selected and divided into observation group(n=36 cases)and control group(n=36 cases) by table of ran-dom number. The patients in observation group were given propofol and remifentanil, while the patients in control group were given combined anesthesia of propofol and fentanyl. The changes of revival time and cognitive function of patients in two groups after the anesthesia were observed and compared. Results The spontaneous breathing recovery time,eyes-open time,time of extubation and orientation recovery time of patients in observation group after the anes-thesia were all much shorter than those in control group (P<0.05 or P<0.01). After comparing the MMSE scores of pa-tients in two groups before anesthesia, no statistical differences appeared (P>0.05). The MMSE scores at 6 and 12 hours after the anesthesia obviously declined than before(P<0.05 or P<0.01),and the declining rate of patients in ob-servation group was much lower than that in observation group (P<0.05). The MMSE score at 24 hours after the anes-thesia came back to the same level as that before anesthesia(P>0.05). Conclusion Compared with combined anesthesia of propofol and fentanyl, the revival time, tracheal intubation time and postoperative recovery monitoring time of pa-tients,who are given the combined anesthesia of propofol and remifentanil,are all much shorter,and the influence on cognitive function after anesthesia is much smaller for senile patients.
