comparative study of non-invasive fibrosis serological testing and liver biopsy diagnosis of liver
- VernacularTitle:血清学无创肝纤维化检测与肝脏穿刺病理诊断的比较研究
- Author:
Lingdi WANG
1
;
Ludan WU
;
Weilin MAO
Author Information
1. 宁波市鄞州人民医院病理科
- Keywords:
Chronic hepatitis B;
Liver fibrosis;
Pathology;
Serology
- From:
China Modern Doctor
2014;(24):90-92
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the serological non-invasive liver fibrosis tests and pathological examination in the clinical diagnosis of chronic hepatitis B. Methods Selected 97 patients with chronic hepatitis B in our hospital as the research object and tested non-invasive liver fibrosis tests and liver biopsy pathological examination.Compare the test results of two kinds. Results The serum noninvasive hepatic fibrosis index(PⅢP,Ⅳ-C,HA,LN)showed good positive correlation with pathological stage. The correlation coefficient suggested that with the aggravation of hepatic fibrosis,liv-er fibrosis indexes tended to rise gradually,and the indicators differences were statistically significant (P<0.05). Con-clusion Liver biopsy in patients with chronic hepatitis B diagnosis detection is the "gold standard" with greater injury. Serological non-invasive liver fibrosis tests has high diagnostic value,can reduce the number of puncture biopsy.
