Expression of HCCR, pERK, pELK1 in gastric cancer and its correlations
- VernacularTitle:HCCR、pERK及pELK1蛋白在胃癌组织中的表达及其相关性
- Author:
Linhua YAO
1
;
Yi HU
;
Zhongmin DENG
;
Ling ZHANG
;
Guoxin ZHANG
Author Information
1. 湖州师范学院附属第一医院消化内科
- Keywords:
Gastric cancer;
HCCR;
pERK;
PELK1
- From:
China Modern Doctor
2014;(24):1-3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expression of HCCR, pERK and pELK1 in gastric cancer tissue and para-carci-noma tissue, and to explove its correlations. Methods In 60 human gastric cancers and their corresponding paraneo-plastic tissuses,the expression of HCCR, pERK and pELK1 were detected by immunohistochemistry. Results The ex-pression of HCCR was 75.0%(45/60), pERK, and pELK1 were 73.3%(44/60) and 71.7%(43/60), respectively, and the expression of proteins in gastric tumor were higher than that in paraneoplastic tissues (P<0.05). Conclusion The HCCR, pERK and pELK1 are higher expressed in tumor tissues, availably as a auxiliary index for clinical immunohis-tochemistry in gastric cancer.
