Value analysis of cystatin C, β2-microglobulin and microalbuminuria in the diagnosis of early renal damage
- VernacularTitle:胱抑素C、β2-微球蛋白及尿微量清蛋白在早期肾损害诊断中的应用价值分析
- Author:
Suqin XU
1
;
Ping ZHANG
Author Information
1. 浙江省义乌复元私立医院检验科
- Keywords:
Cystitis C;
β2-macroglobulin;
Microalbuminuria;
Early renal damage
- From:
China Modern Doctor
2014;(23):158-160
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the value of cystatin C, β2-microglobulin and microalbuminuria in the diagnosis of early renal damage. Methods Hospital urologist admitted 150 patients with early renal damage as the observation group, selected 150 cases of normal adults in our hospital as the control group, cystatin C, β2-microglobulin and mi-croalbuminuria were measured in the two groups, and the diagnostic value of three markers alone or in combination de-tection were compared. Results The cystatin C, β2-microglobulin and microalbuminuria levels in observation group were significantly higher than control group, sensitive rate of cystatin C, β2-microglobulin and microalbuminuria and joint detection degrees were 91.33%,88.00%, 94.00% and 98.00%; Specificity was 88.00%, 91.33%, 92.00%, 95.33%;Youden indexes were 0.79, 0.79, 0.86, 0.93. Conclusion Cystitis C,β2-microglobulin and microalbuminuria have some diagnostic value in the diagnosis of early renal damage, three markers combined detection can improve diagnostic accu-racy and specificity, worthy of promotion.
