Primary breast lymphoma:A clinical analysis of 25 cases
- VernacularTitle:原发性乳腺淋巴瘤25例临床分析
- Author:
Fenglian JIANG
1
;
Weijian SHI
;
Wendong JU
;
Qiaoyun ZHOU
;
Quanyong LI
;
Li WANG
;
Haojie SONG
Author Information
1. 广东省中山市博爱医院肿瘤内科
- Keywords:
Primary breast lymphoma;
Clinical features;
Prognosis
- From:
China Modern Doctor
2014;(23):141-144
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the recognition and management of primary breast lymphoma(PBL) by discussing the clinical pathological characteristics and the prognosis of PBL. Methods The clinical and treatment records of PBL pa-tients admitted in Boai hospital of zhongshan from January 2001 to December 2012 were analyzed. Results All cases were B-cell origin(25/25),61.5%(16/25)were diffuse large B-cell lymphoma origin,The 5-year overall survival was 44%. There were no significant difference in the 5-year overall survival rates, 5-year local control rates and 5-year distant control rates in patient treatment with any surgery compared with no-Surgery(P>0.05).There were no significant difference in the 5-year overall survival rates and 5-year distant control rates in patient treatment with any RT com-pared with no-RT(P>0.05),but the 5-year local control rates was significantly different(P<0.05);There were no sig-nificant difference in the 5-year overall survival rates and 5-year local control rates in patient treatment with any chemotherapy compared with no-chemotherapy (P>0.05). but the 5-year distant control rates was significant different(P<0.05). Conclusion The prognosis of PBL is related with the clinical stage and pathological type. Radiotherapy and chemotherapy respectively promote the local control and distant control. The optimal treatment is surgery combined with chemotherapy and/or radiotherapy.