The clinical effects of propofol and etomidate in patients with general anesthesia
- VernacularTitle:丙泊酚与依托咪酯对全麻患者临床效应的比较
- Author:
Ke LIU
1
;
Yaping LU
;
Lan LAI
;
Xuyan ZHOU
;
Ming YAO
Author Information
1. 浙江省嘉兴市第一医院麻醉科
- Keywords:
Etomidate;
Propofol;
General anesthesia induction;
Hemodynamic;
Adverse reactions
- From:
China Modern Doctor
2014;(23):55-57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of propofol and etomidate for anesthesia induction on hemodynamics and adverse reactions during the perioperative period. Methods One hundred patients undergoing elective abdominal surgery were randomly divided into the propofol group (Group P) and etomidate group(Group E). For anesthesia induc-tion, successively injected midazolam-propofol-fentanyl-rocuronium in Group P, and the propofol was replaced by eto-midate in Group P. The circulation,stress and the adverse reactions before induction(T0), before intubation(T1), 3 min after intubation (T2), two groups were recorded. Results Compared with the P group, the T1 SBP, HR, T2 SBP, DBP, and HR were higer in E group; The incidence of injection pain was higher in Group P , but the incidence of muscle tremors was lower in Group P(P<0.05). Conclusion The etomidate is more suitable for the patients with hemodynamic instability. Both etomidate and propofol has no effect on blood sugar.
