The clinical efficacy of small doses of interferon antiviral in treatment of chronic hepatitis with decompensated cirrhosis
- VernacularTitle:小剂量干扰素抗病毒治疗慢性丙型肝炎肝硬化失代偿期的临床疗效
- Author:
Zhuoling LIU
1
Author Information
1. 湖南省湘潭市中心医院感染科
- Keywords:
Chronic hepatitis C;
Cirrhosis;
Decompensation;
Small doses of interferon antiviral;
Antiviral
- From:
China Modern Doctor
2014;(23):31-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical efficacy of small doses of interferon antiviral in treatment of chronic hep-atitis with decompensated cirrhosis. Methods Forty cases with chronic hepatitis with decompensated cirrhosis were se-lected from our hospital during the period from June 2012 to June 2013,all patients were given ribavirin and small doses of interferon,all patients were followed up 24 weeks after treatment. Results Twenty-nine cases of 40 patients were insisted in antiretroviral therapy,17 patients were treated for 24 weeks,12 patients were treated for 48 weeks. Af-ter treatment, the anorexia and bloating symptoms of 29 patients were vary degrees of ease. The liver function index(ALT,AST,ALB,TB),coagulation (PTA) and virological indicators in 24 weeks were significantly improved,the differ-ence was statistically significant (P<0.05);72 weeks compared with 48 weeks,the liver function index(ALT,AST,ALB, TB), coagulation (PTA) and virological indicators had no significantly improved,the difference was not statistically significant(P>0.05). Conclusion Interferon antiviral has better clinical effect in treatment of chronic hepatitis,and it can improve the liver function.
