Early diagnostic value of serum procalcitonin combined with kidney in-jury molecule-1 (kim-1) for children sepsis complicated with acute kidney injury
- VernacularTitle:血清降钙素原联合尿液肾损伤分子-1（KIM-1）对小儿脓毒血症并发急性肾损伤的早期诊断价值
- Author:
Yue ZHAO
1
;
Qiang LIU
;
Xi LIU
;
Ying XU
;
Xianou HONG
Author Information
1. 深圳市宝安区妇幼保健院PICU
- Keywords:
Serum procalcitonin;
Kidney injury molecule-1 (KIM-1);
Children sepsis;
Acute kidney injury
- From:
China Modern Doctor
2014;(23):16-18
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of serum procalcitonin and KIM-1 and their significance for early diag-nosis of sepsis complicated with acute kidney injury (AKI). Methods A total of 54 children patients with sepsis who were admitted to PICU in the department of pediatrics in our hospital were allocated to AKI group with 30 patients and non-AKI group with 24 patients according to the diagnostic criterion of AKI; 24 healthy children were selected as a control group. Serum procalcitonin and urine KIM-1 were measured in the three groups. Results Levels of serum pro-calcitonin and urine KIM-1 in patients among the healthy group, non-AKI group and AKI group showed significant differences. Conclusion Serum procalcitonin and urine KIM-1 can be used as early diagnostic markers for children sepsis complicated with acute kidney injury.
