The construction of PSGL-1+/-;IL-2-/-mice model
- VernacularTitle:PSGL-1+/-；IL-2-/-小鼠模型的构建
- Author:
Cuiling QI
1
;
Jie YE
;
Yang YANG
;
Bin LI
;
Xiaodong HE
;
Jiangchao LI
;
Qianqian ZHANG
;
Ren HUANG
;
Lijing WANG
Author Information
- Keywords: PSGL-1; IL-2; PSGL-1 knockout mice; IL-2 knockout mice; Animal model
- From: China Modern Doctor 2014;(23):7-9
- CountryChina
- Language:Chinese
- Abstract: Objective To construct the PSGL-1+/-;IL-2-/-mice model. Methods PSGL-1 KO mice were mated with IL-2 KO mice. Mice were genotyped by PCR after cut the tail and extracted DNA. Results After PSGL-1 KO mice being mated with IL-2 KO mice for three generations, PSGL-1+/-;IL-2-/-mice were obtained. Conclusion PSGL-1+/-;IL-2-/-mice are established through PSGL-1 KO mice being mated with IL-2 KO mice.
