A control study on agomelatine and paroxetine in treatment of senile de-pression
- VernacularTitle:阿戈美拉汀与帕罗西汀治疗老年抑郁症对照研究
- Author:
Zhijun YU
1
;
Xianwei YAO
;
Hongshan PAN
;
Cuiying MO
;
Xin DUAN
;
Chunyang LI
Author Information
1. 广东省佛山市顺德区伍仲珮纪念医院药械科
- Keywords:
Agomelatine;
Paroxetine;
Senile depression
- From:
China Modern Doctor
2014;(20):41-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy and safety of agomelatine and paroxetine for the senile depression. Methods A total of 98 cases of elderly patients diagnozed with depression were randomly divided into two groups, one group were treated with agomelatine,the other group were treated with paroxetine,treated for 6 weeks, using Hamilton depression scale(HAMD), adverse reaction scale(TESS) to evaluate the efficacy and adverse reactions. Results After 6 weeks of treatment, the HAMD scores showed that there were no significant differences in clinical efficacy of two groups, and the TESS showed the agomelatine had less adverse reaction than the paroxetine. Conclusion Agomelatine is a safe and effective antidepressant , suitable for elderly patients.
