Evaluation of thin prep cytology test in transbronchial needle aspiration for diagnosis of lung cancer
- VernacularTitle:液基细胞学在经支气管镜针吸细胞学诊断肺癌中的价值
- Author:
CHEN Dan LV
1
;
Zhongbo
;
Zaichun DENG
Author Information
1. 宁波大学医学院附属医院呼吸内科
- Keywords:
Central lung cancer;
Thin prep cytology;
Conventional smear;
Transbronchial needle aspiration
- From:
China Modern Doctor
2014;(20):9-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of thin prep cytology test(TCT) in central lung cancer. Methods All 127 patients suspected central lung cancer were detected by transbronchial needle aspiration(TBNA). The patients were randomly assigned into two groups, the group of conventional smear,CS (62 cases) and the group of CS+TCT(65 cases). The sensitivity and specificity of two methods were compared. Results The sensitivity and specificity of CS were 75.9%and 100.0% respectively. The sensitivity and specificity of CS+TCT were 96.2% and 100.0% respectively. The sensitivity of CS+TCT was significantly higher than sensitivity of CS in diagnosis of lung cancer (P=0.000046<0.01). Conclusion Combination of CS and TCT techniques can improve the TBNA diagnostic sensitivity of lung cancer. TBNA-TCT detection methods should be applied to clinical activites.