TNFα, SP-A expression and clinical significance of varying degrees of pneumonia in children
- VernacularTitle:TNF-α、SP-A在儿童不同程度肺炎中的表达和临床意义
- Author:
Jialei ZHOU
1
;
Dongxin XU
;
Yi LI
;
Zhimin CHEN
Author Information
1. 杭州市萧山区第一人民医院检验科
- Keywords:
Child pneumonia;
TNF-α;
SP-A;
Serum
- From:
China Modern Doctor
2014;(18):145-147
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression levels change and it's clinical significance of TNF-α, SP-A in chil-dren with varying degrees of pneumonia. Methods A total 195 cases of pneumonia children patients were divided into ordinary pneumonia and severe pneumonia patients , another 65 cases of non-pneumonic children patients as the con-trol group, ELISA assay was used to detect serum TNF-α and SP-A level. Results The levels of serum SP-A and TNF-αof pneumonia children group were higher than the control group's , and severe pneumonia patients ’ were high-er than ordinary pneumonia. Conclusion The expression level of TNF-α and SP-A increased significant in the patho-genesis of children with severe pneumonia which could reflect the degree of lung injury and as a indicator in clinical testing.
