Clinical research on hepatic artery intervention combining targeted thera-py on 80 patients with hepatic metastasis of colonic carcinoma
- VernacularTitle:肝动脉介入联合靶向治疗结肠癌肝转移80例临床研究
- Author:
Quanzhong YE
1
;
Jin CHENG
;
Yinchu ZHAN
Author Information
1. 浙江省衢州市人民医院消化科
- Keywords:
Hepatic artery intervention;
Targeted therapy;
Hepatic metastasis of colonic carcinoma
- From:
China Modern Doctor
2014;(18):26-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study clinical effects and adverse reactions of hepatic artery intervention combining targeted therapy on hepatic metastasis of colonic carcinoma. Methods Eighty cases of patients with hepatic metastasis of colonic carcinoma, patients in the control group were selected, patients in the control group were subject to hepatic artery in-tervention therapy according to different methods of treatment , and patients in the observation group were subject to targeted therapy on the basis of that applied to patients in the control group , clinical effects and adverse reactions of patients in two groups were observed. Results The comparison in the total effective rate of patients in two groups (χ2=6.9520,P=0.0084), and the comparison in one-year survival rate of patients in two groups(χ2=4.7760,P=0.0289), the comparison in two-year survival rate of patients in two groups (χ2=5.6144,P=0.0178), the comparison in three-year survival rate of patients in two groups(χ2=4.3988,P=0.0360), and the comparison in five-year survival rate of patients in two groups (χ2=4.4443,P=0.0350), the differences were statistically significant. The comparison in adverse reaction of patients in two groups was not significantly different. Conclusion The hepatic artery intervention combining targeted therapy on hepatic metastasis of colonic carcinoma delivers great effect and significantly prolong the life of patients , being worthy of clinical application.
