Study of bletilla striata gelatin loaded macromolecular nerve growth fac-tor in treatment of deep pressure sore
- VernacularTitle:白芨胶载高分子神经生长因子治疗深度压疮的研究
- Author:
Peigeng MA
1
;
Jianzhong LIAO
;
Xuefen ZHUANG
Author Information
1. 深圳市龙岗区第二人民医院骨科
- Keywords:
Bletilla striata gelantin;
Macromolecular nerve growth factor;
Deep pressure sore
- From:
China Modern Doctor
2014;(14):50-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of bletilla striata gelantin (BSG) loaded exogenous high molecular weight (HMW) nerve growth factor (NGF) in the promotion of deep pressure sore healing. Methods The patients with deep pressure sore were randomly divided into four group: group A, as the control group, used iodophor-soaked sterile gauze for continuous wet compressing; group B, group C and group D, as the experiment group, received external application of BSG, HMW-NGF and HMW-NGF+BSG 3 times per day. The observation indicators included the pressure sore healing velocity, healing time, general reactions and local skin inflammatory reactions during medication on day 3, 7, 14, 21 and 30 of medication. Results BSG, HMW-NGF and HMW-NGF+BSG could all promote the wound healing of pressure sore and HMW-NGF+BSG has the most remarkable effect (healing days: A∶B∶C∶D=20.16 ± 4.58∶15.43±1.72∶15.80±1.48∶11.86±1.35d). Conclusion HMW-NGF+BSG can obviously accelerate the wound healing of pressure sore.
