Expression and significance of Bcl-2 and S100A6 in human uterine smooth muscle tumors
- VernacularTitle:Bcl-2与S100A6在不同子宫平滑肌肿瘤中的表达及意义
- Author:
Tingting SONG
1
;
Meirong LI
;
Yaling WANG
Author Information
1. 山西医科大学
- Keywords:
Human uterine smooth muscle tumors;
Bcl-2;
S100A6
- From:
China Modern Doctor
2014;(14):42-44
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and meaning of Bcl-2 and S100A6 protein in human uterine smooth muscle tumors. Methods Immunohistochemical technique was used to detect the Bcl-2 and S100A6 protein ex-pressions:30 usual leiomyoma (UL),10 leiomyosarcoma (LMS) and 30 cellular leiomyoma (CL). Results The positive Bcl-2 protein expression rate of UL and CL was apparently higher than that of LMS (P<0.05),the Bcl-2 protein ex-pression were statistical difference in UL and CL; the positive S100A6 protein expression rate of LMS was apparently higher than that of UL(P<0.05),the positive S100A6 protein expression rate of LMS was apparently higher than that of CL(P<0.05). Conclusion The expression of Bcl-2 or S100A6 protein may play an important role in the occurrence and development of human uterine smooth muscie tumors.
