The Early Diagnosis and Clinical Analysis of 19 Cases of Multiple System Atrophy
10.3969/j.issn.1673-9701.2009.18.006
- VernacularTitle:19例多系统萎缩临床分析及早期诊断
- Author:
Pinghua YANG
1
;
Jian HUANG
;
Zhongxin ZHAO
Author Information
1. 上海市浦东新区公利医院
- Keywords:
Multiple system atrophy;
Clinical analysis;
Early diagnosis
- From:
China Modern Doctor
2009;47(18):12-14,27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical manifestations of multiple system atrophy(MSA), and assess the significance of the assistant examination for the early diagnosis. Methods The clinical and assistant examination data of 19 cases of MSA were retrospectively analyzed. Results Multiple system atrophy comprise a diverse group of diseases which slowly onset,and gradually increase. The clinical manifestations were autonomic nerve dysfunction,cerebellar ataxia and Parkinsonism.The autonomic nerve symptoms were the early clinical manifestation,and the extrapyramidal symptoms were the optima frequent motion abnormality.These were the two main reasons for MSA to be misdiagnosised. Brain atrophy brain atrophy and hypometabolism of glucose were detected in the Neuroimaging imaging. Anal sphincter(EAS) eletromyography(EMG) was sensitive and specific. Conclusion Clinical manifestations of this disease are complex and diverse early in the disease,we often misdiagnosed.Based on detailed medical history and comprehensive examination of the nervous system,and supplemented by relevant inspection,we can improve the accuracy of early diagnosis of MSA.
