Effect of Percutaneous Electrical Stimulation of Acupuncture Points on Blood Oxygen Free Radical Induce by Ischemia-reperfusion Injury in Limbs
10.3969/j.issn.1673-9701.2009.18.002
- VernacularTitle:经皮穴位电刺激对肢体缺血再灌注损伤氧自由基系统的影响
- Author:
Jinping HUANG
1
;
Zhiqiang XING
Author Information
1. 广东省佛山市南海里水医院
- Keywords:
Transcutaneous electrical stimulation of acupuncture points;
Ischemia-reperfusion injury;
Oxygen free radical;
MDA;
GSH;
SOD
- From:
China Modern Doctor
2009;47(18):4-5
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of pereutaneous electrical stimulation of acupuncture points on blood oxygen free radical induce by ischemia-reperfusiou injury in limbs. Methods 30 patients who received the unilateral lower limb surgery were randomly allocated to A and B groups equality. All the patients were received spinal-epidural anesthesia. Before the anesthesia,B groups patients were stimulated bilateral at NeiGuan and WaiGuan acupuncture points by HAN stimulate instruction until the end of the operation. The concentration of malondialdehyde(MDA), glutathione(GSH) and superoxide dismutase(SOD) were measured by venous blood draw from their elbow in four different periods-before the anesthesia(T0), 10 minutes after the tourniquet released(T1), 30 minutes after the tourniquet released(T2) and 60 minutes after the tourniquet released(T3) respectively. Results Gender, age, weight and the time of using tourniquet shows no different between-group differents. There is also no significant different between two groups before theanesthesia in MDA, GSH and SOD. The two groups all shows obviously increase of MDA(P<0.01) and significant decrease of GSHand SOD (P<0.01) in T1, T2 and T3 in contrast to in T0 compare with the A group, B group shows a significant decrease of MDA (P<0.01) and a significant increase in GSH and SOD (P<0.01) in T1,T2,T3. Conclusion The percutaneous electrical stimulation of acupuncture points can protect the limb by ischemia-reperfusion injury.
