A Case of Hypereosinophilic Syndrome Presenting With Multiorgan Infarctions Associated With Disseminated Intravascular Coagulation.
10.4168/aair.2012.4.3.161
- Author:
Sun Mi PARK
1
;
Ji Won PARK
;
Sung Min KIM
;
Eun Hee KOO
;
Jin Young LEE
;
Chul Su LEE
;
Dong Chull CHOI
;
Byung Jae LEE
Author Information
1. Division of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. leebj@skku.edu
- Publication Type:Case Report
- Keywords:
Hypereosinophilic syndrome;
eosinophilia;
thromboembolism;
disseminated intravascular coagulation;
consumptive coagulopathy;
interferon-alpha
- MeSH:
Adrenal Cortex Hormones;
Cerebral Hemorrhage;
Dacarbazine;
Disseminated Intravascular Coagulation;
Eosinophilia;
Female;
Hematologic Tests;
Hemoptysis;
Humans;
Hypereosinophilic Syndrome;
Infarction;
Interferon-alpha;
Splenic Infarction;
Thromboembolism;
Thrombosis;
Young Adult
- From:Allergy, Asthma & Immunology Research
2012;4(3):161-164
- CountryRepublic of Korea
- Language:English
-
Abstract:
Thromboembolism is one of the most critical complications of hypereosinophilic syndrome (HES). We report here a case of multi-organ infarctions related to HES. A 23-year-old woman was referred to our hospital with hemoptysis. Not only pulmonary, but also renal and splenic infarctions were detected on computed tomography images. Blood tests showed profound peripheral eosinophilia. She was diagnosed with HES with disseminated intravascular coagulation (DIC). We initiated infusion of corticosteroids, which effectively suppressed peripheral eosinophilia. However, consumptive coagulopathy did not improve and intracerebral hemorrhage related to thrombosis then developed. Addition of interferon-alpha resulted in the correction of the DIC associated with HES.
