Characterization of Diabetic Nephropathy and Its Correlates in a  Selected Outdoor-Based Diabetic Clinic in Rangpur, Bangladesh

Zannatul Ferdous; Abdur Rahman; Ruhul Furkan Siddique; Abdul Halim; Sheikh Jafia Jafrin

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Characterization of Diabetic Nephropathy and Its Correlates in a Selected Outdoor-Based Diabetic Clinic in Rangpur, Bangladesh

Author: Zannatul Ferdous ¹ ; Abdur Rahman ¹ ; Ruhul Furkan Siddique ¹ ; Abdul Halim ² ; Sheikh Jafia Jafrin ³
Author Information

1. Department of Public Health and Informatics, Jahangirnagar University, Savar, Dhaka-1342 Bangladesh.
2. Research and Development Analytical, Incepta Pharmaceutical Ltd
3. Department of Geological Sciences, Jahangirnagar University, Savar, Dhaka-1342.
Publication Type:Journal Article
Keywords: Type 1 diabetes; type 2 diabetes; diabetic nephropathy; estimated glomerular filtration rate; Albumin to Creatinine ratio; Bangladesh
From:International Journal of Public Health Research 2021;11(2):1388-1396
CountryMalaysia
Language:English
Abstract: Introduction:Diabetes mellitus (DM) is a global public health problem. DM is associated with the rising burden of diabetic complications. Diabetic nephropathy (DN) is one of the life-threatening and irreversible microvascular complications of DM.
Methods:A cross-sectional study was conducted from November 2017 to April 2018. This study aimed to characterize the proportion of DN among people living with diabetes (n=290, where 40 T1DM, 200 T2DM as cases group and 50 nondiabetic as a control group) and the factors associated with it. The sample was selected using convenience sampling. Data were collected using structured questionnaire and analyzed by SPSS-22. Stages of DN were classified according ‘Revised Classification of DN’ given by the ‘Joint Committee on Diabetic Nephropathy’, Japan, 2014.
Results:The proportion of pre-nephropathy (PN), incipient nephropathy (IN) and overt nephropathy (ON) was 10%, 82.5% and 7.5% respectively in T1DM. Similarly, in T2DM the proportion of PN, IN, ON and chronic kidney failure (CKF) was 5.5% 81%, 10%, and 3.5% respectively. Irrespective of diabetic group, according to multivariate analysis, older age (adjusted OR =1.05, CI: 1.01-1.08; adjusted OR: 2.33, CI: 2.01-2.99), and female sex (adjusted OR = 0.39, CI: 0.19-0.77) were independently associated with DN adjusting BMI, SBP, DBP and FBS level.
Conclusions:This study showed the proportion of DN was high among diabetic and mostly in type 2 diabetics with severe stage. Older age, and female sex were independently associated with DN.
Full text:202407010935427601321.2021my0261.pdf