Coincidental finding of Sertoli-Leydig Cell Tumor in a postmenopausal woman with mild hyperandrogenism, ovarian teratoma, and pelvic organ prolapse: A case report
- Author:
Hermina Silonga-Arce
1
;
Minnou O. Tapia
1
Author Information
- Publication Type:Case Reports
- Keywords: Mature cystic teratoma; Hyperandrogenism
- MeSH: Sertoli-Leydig Cell Tumor
- From: Philippine Journal of Reproductive Endocrinology and Infertility 2024;21(1):8-13
- CountryPhilippines
- Language:English
- Abstract: A Sertoli-Leydig cell tumor (SLCT) is an extremely rare type of sex cord stromal tumor of the ovary, which mainly secretes testosterone, thus manifestations of hyperandrogenism commonly appear. This paper shall discuss a case of a postmenopausal woman who presented with pelvic organ prolapse, large left ovarian cyst and mild signs of hyperandrogenism. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, which on microscopic examination of the specimens, revealed a Mature cystic teratoma on the left ovary and an incidental finding of a well-differentiated SLCT, on the grossly normal-looking ovary. This histopathologic diagnosis of SLCT explained the patient’s hyperandrogenic characteristics. Authors likewise discussed the proper management of SLCT, including immunostaining and need for adjuvant chemotherapy.
- Full text:2024062713270278612Coincidental Finding.pdf
