Accuracy of Quick Sequential Organ Failure Assessment (qSOFA) scoring as in-hospital mortality predictor in adult patients with sepsis secondary to urinary tract infection admitted in a local tertiary hospital in Davao City: A cross-sectional study
- Author:
Angela Libby Y. Tan
1
;
Jose Paolo P. Panuda
1
Author Information
- Publication Type:Journal Article
- Keywords: qSOFA; UTI
- MeSH: Sepsis; Urinary Tract Infections; Hospital Mortality
- From: Philippine Journal of Internal Medicine 2024;62(2):93-99
- CountryPhilippines
- Language:English
-
Abstract:
Background:The quick Sequential Organ Failure Assessment (qSOFA) score was introduced by Sepsis-3 or the Third International Consensus Definitions for Sepsis and Septic Shock to help physicians in identifying patients outside the intensive
care unit with suspected infection who are at high risk for in-hospital mortality. However, sepsis is not a homogenous entity
and the outcomes vary based on several factors. This study aimed to determine the predictive accuracy of qSOFA in identifying those at high-risk of in-hospital mortality among adult patients with sepsis secondary to urinary tract infection.
Methodology:A retrospective cohort study was done involving the use of qSOFA score to predict in-hospital mortality of adult patients with a diagnosis of sepsis secondary to urinary tract infection, admitted in the hospital from January 1, 2013 to December 31, 2020. qSOFA is computed based on the following independent variables: systolic blood pressure (SBP), respiratory rate (RR), and Glasgow Coma Scale (GCS).
Results:Of the 128 charts retrieved, 121 patients were included in the study. Fifteen (12.40%) died while 106 (87.60%) survived. Mean age was 60.76 years old, with more females (71.90%) than males (28.10%). Hypertension and Diabetes Mellitus Type 2 were the most frequent comorbidities. Complicated UTI was the most frequent source of infection. Mean length of stay was 8.29 days. Forty (33.06%) patients had qSOFA ≥ 2 wherein 11 (27.5%) died. Diagnostic performance results revealed: sensitivity (73.33%), specificity (72.64%), positive (27.5%) and negative (95.06%) predictive values, and positive (2.68) and negative (0.37) likelihood ratios. qSOFA accuracy was 72.73% with an AUROC of 0.76.
Conclusion:Among the admitted adult patients with sepsis secondary to a UTI, qSOFA had a good prognostic accuracy for in-hospital mortality. - Full text:20240627121140867814 2023-235 OK.pdf
