Recent advance in cell membrane-modified nanoparticles for malignant brain tumor
10.3760/cma.j.cn115354-20240104-00013
- VernacularTitle:细胞膜修饰纳米粒子治疗脑部恶性肿瘤的研究进展
- Author:
Jing YANG
1
;
Yichu SUN
;
Fei LIANG
;
Ziqiang SHEN
;
Youyou XIA
Author Information
1. 徐州医科大学附属连云港医院（连云港市第一人民医院）肿瘤放疗科，连云港 222000
- Keywords:
Cell membrane modification;
Nanoparticle drug delivery system;
Brain;
Malignant brain tumor;
Blood-brain barrier;
Targeted therapy
- From:
Chinese Journal of Neuromedicine
2024;23(2):186-191
- CountryChina
- Language:Chinese
-
Abstract:
Cell membrane-modified nanoparticles (NPs) have attracted widespread attention as a new approach for malignant brain tumors in recent years. This method can enhance the targeting, biocompatibility, and circulation time of NPs by preserving the characteristics of source cell membrane, thereby ensuring efficient drug delivery to intracranial lesions. This paper focuses on the research progress in this field, especially advantages of NPs penetrating the blood-brain barrier, immune evasion and drug delivery, as well as modified effect of different cell membrane on NPs, in order to provide help for treatment of malignant brain tumors.
