Recent advance in Tau proteinopathy and circulatory disturbance of synaptic vesicles
10.3760/cma.j.cn115354-20221030-00763
- VernacularTitle:Tau蛋白病与突触囊泡循环障碍的研究进展
- Author:
Yutong WEN
1
;
Yu XIAO
;
Yueqin TIAN
;
Xiaoya GAO
Author Information
1. 南方医科大学第二临床医学院，广州 510280
- Keywords:
Tau proteinopathy;
Synaptic vesicle cycle;
Synaptic vesicle transmission;
Alzheimer's disease;
Progressive supranuclear palsy
- From:
Chinese Journal of Neuromedicine
2023;22(10):1054-1058
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies have found that the pathological changes of Tau proteinopathy, such as Alzheimer's disease (AD) and progressive supranuclear palsy (PSP), involve transmission or circulatory disturbance of synaptic vesicles. This article reviews the relations of AD/PSP with circulatory disturbance of synaptic vesicles and explore the pathogenesis of these diseases, aiming to provide a new perspective for new therapeutic drugs.
