Recent advance in pathogenesis of osteoporotic fracture in patients with Parkinson's disease
10.3760/cma.j.cn115354-20230113-00023
- VernacularTitle:帕金森病患者骨质疏松性骨折的发病机制研究进展
- Author:
Yiman XIE
1
;
Ziqi HUANG
;
Jing WANG
;
Nanqu HUANG
;
Yong LUO
Author Information
1. 遵义医科大学第三附属医院（遵义市第一人民医院）血管超声室，遵义 563000
- Keywords:
Parkinson's disease;
Osteoporotic fracture;
Pathogenesis
- From:
Chinese Journal of Neuromedicine
2023;22(10):1049-1053
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, a large number of studies have found that Parkinson's disease (PD) patients often complicate with osteoporotic fracture, which may be related to decreased dopamine transmitters, PD risk gene mutations, mitochondrial dysfunction, vitamin D reduction, anti-PD drug use, autonomic nervous dysfunction and intestinal microflora disorders. Therefore, this paper reviews the current research progress on the pathogenesis of osteoporotic fracture in PD patients to provide theoretical basis for co-morbid treatment of PD and osteoporotic fracture.
