Recent advance in neural networks of placebo analgesia and nocebo hyperalgesia
10.3760/cma.j.cn115354-20221105-00799
- VernacularTitle:安慰剂镇痛和反安慰剂致痛的神经网络研究进展
- Author:
Yu ZHANG
1
;
Wanbin HUANG
;
Zheman XIAO
Author Information
1. 武汉大学人民医院神经内科，武汉 430060
- Keywords:
Placebo;
Nocebo;
Electroencephalograph;
Functional magnetic resonance imaging;
Neural network
- From:
Chinese Journal of Neuromedicine
2023;22(8):838-843
- CountryChina
- Language:Chinese
-
Abstract:
In clinical trials and animal models, indolent substances have been observed to induce pain relief (placebo analgesia) or increased pain (nocebo hyperalgesia). In recent years, advances in neurobiology field are not only about simple superposition of psychological mechanisms, but also about complex changes in neural networks. This article summarizes the neurophysiological changes and activated characteristics of brain regions in placebo analgesia and nocebo hyperalgesia, and expounds the underlying mechanisms involved in placebo analgesia and nocebo hyperalgesia in these brain regions, and how different brain regions interact with each other.
