Exosomes derived from neural stem cells regulates neural stem cells and applicates in nervous system diseases
10.3760/cma.j.cn115354-20221206-00886
- VernacularTitle:神经干细胞来源外泌体对神经干细胞的调节及其在神经系统疾病治疗中的应用
- Author:
Jiajun HUANG
1
;
Hengsen CAI
;
Zhihan ZHU
;
Guilong ZHANG
;
Yifan ZHANG
;
Rong LI
;
Jiale LIU
;
Chenyang GU
;
Jia FENG
;
Lukui CHEN
Author Information
1. 南方医科大学中西医结合医院神经外科，广州 510310
- Keywords:
Neural stem cell;
Exosome;
Neurological disease;
Cell-free therapy
- From:
Chinese Journal of Neuromedicine
2023;22(8):826-832
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, studies have shown that transplanted neural stem cells (NSCs) help neural tissues regenerate and return to normal through paracrine action rather than just replacing cells. Exosomes are essential paracrine mediators that can participate in cell communication through substance transmission. This review focuses on NSCs regulated by exosomes and their application in treatment of nervous system diseases, in order to provide important references for further research and clinical application of NSCs exosomes..
