Recent advance in anxiety related neural circuits regulating by ventral tegmental area
10.3760/cma.j.cn115354-20221101-00782
- VernacularTitle:中脑腹侧被盖区调节焦虑的相关神经环路研究进展
- Author:
Yue QI
1
;
Ziwei ZHANG
;
Guojian ZHAO
;
Suhua YAO
;
Jinhua XUE
;
Xiaolu TANG
Author Information
1. 赣南医学院基础医学院,赣州 341000
- Keywords:
Ventral tegmental area;
Anxiety;
Neural circuit
- From:
Chinese Journal of Neuromedicine
2023;22(7):735-739
- CountryChina
- Language:Chinese
-
Abstract:
As a common emotional and psychogenic disorder, anxiety disorder seriously threats the human physical and mental health. Ventral tegmental area (VTA) is the canter of the mesocortical limbic circuit, with extensive bidirectional connections to forebrain areas, and plays important role in regulating reward, motivation, cognition, and disgust. Besides, VTA is involved in anxiety regulation by forming functional connections with multiple brain regions and connecting external stimulus information and feedback output behaviours. This article briefly summarizes the different cell subsets of VTA and its involvement in anxiety-related neural circuits.