Gene transcriptome sequencing in schizophrenia
10.3760/cma.j.cn115354-20220911-00630
- VernacularTitle:转录组测序技术在精神分裂症中的研究应用
- Author:
Bolun ZHANG
1
;
Ao GAO
;
Yina LU
;
Chunyue HUO
Author Information
1. 首都医科大学燕京医学院，北京 101300
- Keywords:
Schizophrenia;
Transcriptome sequencing;
Gene differential expression
- From:
Chinese Journal of Neuromedicine
2023;22(5):518-522
- CountryChina
- Language:Chinese
-
Abstract:
Schizophrenia is a mental illness that can seriously affect a patient's cognitive and social communication. Because schizophrenia is affected by multiple factors, the cause of schizoophrenia is still unclear. Gene transcriptome sequencing (RNA-seq) is a new research method to study the morphological structure, and gene differential expression and function; RNA-Seq can sequence hundreds of thousands to millions of DNA molecules at a time, providing more effective data for biological transcription information. This paper reviews the principles and technical characteristics of RNA-Seq, and application of RNA-Seq in schizophrenia, which provide new ideas for schizophrenia research.
