Characteristics of acute symptomatic seizures and autoimmune associated epilepsy secondary to autoimmune encephalitis

VernacularTitle:继发于自身免疫性脑炎的急性症状性癫痫发作和自身免疫相关性癫痫的特点分析
Author: Yun ZHANG ¹ ; You WANG ; Yangmei CHEN
Author Information

1. 重庆医科大学附属第二医院神经内科，重庆　400000
Keywords: Autoimmune encephalitis; Epilepsy seizure; Acute epileptic seizures secondary to autoimmune encephalitis; Autoimmune associated epilepsy
From: Chinese Journal of Neuromedicine 2023;22(3):306-310
CountryChina
Language:Chinese
Abstract: Autoimmune encephalitis (AE) is closely related to epileptic seizure, which is a common clinical manifestation or even the only symptom at acute phase of AE. Most patients do not develop seizures after treatment at acute or subacute stages, and these patients are classified as acute symptomatic seizures secondary to AE (ASSAE). Only a minority of patients will eventually develop autoimmune associated epilepsy (AAE). At present, no unified standard for clinical diagnosis is noted between ASSAE and AAE, but some differences exist in definition, pathogenesis, diagnosis and treatment. This paper summarizes the similarities and differences between ASSAE and AAE in the above aspects, aiming at providing help for clinicians to differentiate the diagnosis of the two diseases.