Recent advance in non-drug therapy for paroxysmal sympathetic hyperactivity after brain injury
10.3760/cma.j.cn115354-20220825-00582
- VernacularTitle:颅脑损伤后阵发性交感神经过度兴奋非药物治疗的研究进展
- Author:
Ling XIAO
1
;
Hong XIONG
;
Xiaolei ZHAO
;
Ruyu LIAO
;
Liping ZENG
;
Qinglian LUO
;
Shengmin GUO
Author Information
1. 西南医科大学护理学院，泸州 646000
- Keywords:
Paroxysmal sympathetic hyperactivity;
Brain injury;
Nutritional support;
Hyperbaric oxygen therapy
- From:
Chinese Journal of Neuromedicine
2023;22(3):301-305
- CountryChina
- Language:Chinese
-
Abstract:
Paroxysmal sympathetic hyperactivity (PSH) is mainly secondary to a variety of acquired brain injuries, with the highest incidence of traumatic brain injury. Multiple symptoms such as paroxysmal tachycardia, shortness of breath, hypertension, hyperthermia and dystonia can occur simultaneously and repeatedly. The pathophysiological mechanism of PSH is complex. At present, drug treatment is mainly used to control symptoms; however, the combined use of multiple drugs will bring different degrees of toxic and side effects to multiple organs such as liver, kidney and lung while inhibiting sympathetic excitement. This paper mainly reviews the recent advance in non-drug treatment of PSH after craniocerebral injury from 4 aspects: nutritional support, hyperbaric oxygen therapy, avoidance of adverse stimulation and family support to standardize the PSH comprehensive management, and reduce episodes in order to improve prognosis and provide reference for clinical treatment.
