Recent advances in behavioral and psychological symptoms of Alzheimer's disease

VernacularTitle:阿尔茨海默病中精神行为症状的研究进展
Author: Anran REN ¹ ; Qihao GUO
Author Information

1. 上海交通大学附属第六人民医院老年病科，上海　201306
Keywords: Alzheimer's disease; Behavioral and psychological symptoms; Dementia
From: Chinese Journal of Neuromedicine 2023;22(2):189-193
CountryChina
Language:Chinese
Abstract: Behavioral and psychological symptoms of dementia (BPSD) is a common symptom of Alzheimer's disease (AD), with an occurrence of 90%. BPSD can lead to poor prognosis and dysfunction in patients with AD, but few safe and effective treatments are available. This article overviews the occurrence frequencies of different manifestations of BPSD in AD and their changes with clinical courses of the disease, and introduces the current research progress on genetic characteristics, pathophysiological mechanism, biomarkers and therapeutics of BPSD in AD to provide references for early recognition and treatment of BPSD in AD.