Recent advance in central nervous regulatory mechanism of transcutaneous auricular vagus nerve stimulation in improving cognitive function

VernacularTitle:经皮耳迷走神经刺激术改善认知功能障碍的中枢神经调节机制研究进展
Author: Xiaocheng LI ¹ ; Lingyan LIANG ; Yichen WEI ; Demao DENG
Author Information

1. 右江民族医学院研究生学院，百色　533000
Keywords: Transcutaneous auricular vagus nerve stimulation; Cognitive function; Central mechanism
From: Chinese Journal of Neuromedicine 2023;22(2):184-188
CountryChina
Language:Chinese
Abstract: Vagus nerve stimulation (VNS) is a neuromodulation technique that achieves therapeutic purpose through intermittent and chronic stimulation of vagus nerve afferent fibers, which has a remarkable effect on functional diseases of the central nervous system, and has been approved by FDA for intractable epilepsy, depression and migraine treatments. Transcutaneous auricular vagus nerve stimulation(taVNS) is a new type of non-invasive nerve regulation therapy based on traditional VNS and vagus nerve anatomy, and has a wide range of central regulation; taVNS can improve the cognitive state by regulating functions of cognition-related cerebral cortex and nerve nuclei, regulating inflammatory response, promoting neurotransmitter transmission, and so on, which has a broad application prospect in cognition-related diseases. This paper mainly summarizes the recent advance in central mechanism of taVNS in improving cognitive function.