Obesity, Inflammation and Diet.
10.5223/pghn.2013.16.3.143
- Author:
Hansongyi LEE
1
;
In Seok LEE
;
Ryowon CHOUE
Author Information
1. Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Korea. rwcho@khu.ac.kr
- Publication Type:Clinical Trial ; Review
- Keywords:
Obesity;
Adipose tissue;
Inflammation;
Diet;
Epidemiology;
Clinical trial
- MeSH:
Abdominal Fat;
Adipokines;
Adiponectin;
Adipose Tissue;
Cardiovascular Diseases;
Cytokines;
Diabetes Mellitus, Type 2;
Diet;
Inflammation;
Interleukin-6;
Interleukins;
Metabolic Diseases;
Necrosis;
Obesity;
Pathologic Processes;
Resistin
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2013;16(3):143-152
- CountryRepublic of Korea
- Language:English
-
Abstract:
Obesity is a state in which there is an over-accumulation of subcutaneous and/or abdominal adipose tissue. This adipose tissue is no longer considered inert and mainly devoted to storing energy; it is emerging as an active tissue in the regulation of physiological and pathological processes, including immunity and inflammation. Adipose tissue produces and releases a variety of adipokines (leptin, adiponectin, resistin, and visfatin), as well as pro- and anti-inflammatory cytokines (tumor necrosis factor-alpha, interleukin [IL]-4, IL-6, and others). Adipose tissue is also implicated in the development of chronic metabolic diseases such as type 2 diabetes mellitus or cardiovascular disease. Obesity is thus an underlying condition for inflammatory and metabolic diseases. Diet or dietary patterns play critical roles in obesity and other pathophysiological conditions. A healthy diet and some nutrients are generally considered beneficial; however, some dietary nutrients are still considered controversial. In this article, dietary factors that influence inflammation associated with obesity are discussed.
