Recent advance in anti-neurexin-3α antibody-associated encephalitis
10.3760/cma.j.cn115354-20220831-00600
- VernacularTitle:抗突触蛋白-3α抗体相关脑炎的研究进展
- Author:
Jiajie CHEN
1
;
Hongyan ZHU
;
Lingchun LIU
;
Hao FU
;
Da LIU
;
Shunyu YANG
;
Ruihan YANG
;
Mingzhi ZHANG
;
Qiang MENG
Author Information
1. 昆明理工大学附属医院 云南省第一人民医院神经内科，昆明 650032
- Keywords:
Neurexin-3α;
Autoimmune encephalitis;
Anti-neurexin-3α antibody-associated encephalitis
- From:
Chinese Journal of Neuromedicine
2023;22(1):84-88
- CountryChina
- Language:Chinese
-
Abstract:
Neurexin-3α, discovered in 2016, is a new type of autoimmune encephalitis antibody. Anti-neurexin-3α antibody-associated encephalitis is generally associated with prodromal symptoms or mood changes, having main clinical manifestations as seizures, memory disorders, confusion or loss of consciousness, central ventilation insufficiency, abnormal behavior, and speech disorders. This paper reviews the relevant research progress at home and abroad about pathogenesis, diagnosis and differential diagnosis, treatment and prognosis of anti-neurexin-3α antibody-associated encephalitis, so as to expand the understanding of clinicians for this disease.
