Recent advance in upstream regulatory mechanism of N6-methyladenin related proteins in glioma

VernacularTitle:胶质瘤中m6A相关蛋白上游调控机制的研究进展
Author: Yi QIN ¹ ; Wei ZHANG ; He HUANG ; Ying ZHANG ; Zhiqian YANG
Author Information

1. 广东药科大学附属第一医院神经外科，广东省垂体疾病干细胞治疗工程技术研究中心，广州　510080
Keywords: Glioma; N6-methyladenin; Micro RNA
From: Chinese Journal of Neuromedicine 2023;22(1):77-83
CountryChina
Language:Chinese
Abstract: Glioma has high incidence and poor prognosis. Glioma pathogenesis is the research hotspot and difficulty in related fields. N6-methyladenin (m6A) is closely related to glioma development, and m6A related proteins play important roles in glioma, which is a potential therapeutic target for glioma. In this paper, the upstream regulatory mechanism of m6A related proteins is reviewed, and the prospect of m6A related proteins as diagnostic markers and potential therapeutic targets for glioma is discussed.