Recent advance in genetic susceptibility and related gene mutations of obstructive sleep apnea syndrome

VernacularTitle:OSAS遗传易感性及相关基因突变的研究进展
Author: Wanqiao QI ¹ ; Yulan ZHU
Author Information

1. 哈尔滨医科大学附属第二医院神经内科，哈尔滨　150001
Keywords: Obstructive sleep apnea syndrome; Genetic susceptibility; Gene mutation
From: Chinese Journal of Neuromedicine 2022;21(11):1178-1183
CountryChina
Language:Chinese
Abstract: Obstructive sleep apnea syndrome (OSAS) is a kind of common sleep disorder, which is characterized by recurrent upper respiratory tract obstruction and decreased arterial oxygen saturation during sleep. At present, the influence of genetic factors in OSAS has been widely recognized, and mutation is one of the important factors for OSAS. So far, the domestic understanding in increase of OSAS genetic susceptibility caused by gene mutation is far from enough. This paper reviews the recent advance in genetic susceptibility and related gene mutations of OSAS at home and abroad in recent years, so as to provide references for further research on pathogenesis of OSAS, and provide new targets for screening, prevention and treatment of OSAS susceptible population in the future.