Recent advance in secondary nerve injury caused by erythrocyte degradation products after intracerebral hemorrhage
10.3760/cma.j.cn115354-20220507-00307
- VernacularTitle:脑出血后红细胞降解产物致继发性神经损伤的研究进展
- Author:
Jun QIN
1
;
Jinbiao XIONG
;
Jiliang HU
Author Information
1. 广西省来宾市人民医院神经外科，来宾 546100
- Keywords:
Intracerebral hemorrhage;
Red blood cell lysis product;
Brain edema;
Neuroinflammation;
Secondary injury
- From:
Chinese Journal of Neuromedicine
2022;21(9):951-955
- CountryChina
- Language:Chinese
-
Abstract:
Intracerebral hemorrhage (ICH) is one of the most devastating diseases in neurosurgery with high mortality and morbidity. Brain edema, neuroinflammation and other related secondary injuries induced by red blood cell lysates such as hemoglobin, bilirubin and peroxidase after intracerebral hemorrhage may be key targets for poor prognosis and treatment; therefore, this article reviews the latest recent advance in the above contents as follows, in order to provide new ideas for the mechanism research and clinical diagnosis and treatment of patients with ICH.
