Changes of electroencephalogram of patients with drug resistant epilepsy after vagus nerve stimulation
10.3760/cma.j.cn115354-20220511-00319
- VernacularTitle:迷走神经刺激术治疗药物难治性癫痫术后脑电图变化特点
- Author:
Shihua DANG
1
;
Lingli JIANG
;
Haifeng SHU
;
Tao YANG
;
Zhi ZHANG
;
Zhichuang QU
;
Sixun YU
;
Xin CHEN
;
Yuan MA
;
Yufang ZHAO
;
Hongmei WANG
Author Information
1. 西部战区总医院神经外科，成都 610083
- Keywords:
Vagus nerve stimulation;
Drug resistant epilepsy;
Electroencephalogram
- From:
Chinese Journal of Neuromedicine
2022;21(9):912-915
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the characteristics and change trends of electroencephalogram (EEG) in patients with drug resistant epilepsy (DRE) after vagus nerve stimulation (VNS).Methods:Twenty-five patients with DRE, admitted to our hospital from July 2016 to May 2019, were chosen; all patients accepted VNS and followed up for 12 months. Long range video EEG (VEEG) monitoring was performed before VNS, and 3, 6 and 12 months after VNS, and the tracing time of each monitoring was longer than 12 h. The EEG characteristics of these patients before and different times after VNS were analyzed.Results:In the VEEG monitoring before VNS, 25 patients showed sharp wave, spike wave, sharp slow wave, and compound spike slow wave in the interictal period; 3 patients (12%) could locate the brain region. The interictal EEG of 11 patients 3 months after VNS showed different degrees of improvement as compared with the preoperative one, which manifested as mixed rhythms: mono-spiking as sharp wave, sharp slow wave or spike wave; 8 patients had McHugh grading I-II. The interictal EEG of 18 patients 6 months after VNS showed different degrees of improvement as compared with the preoperative one; 11 patients had McHugh grading I-II. The interictal EEG of 21 patients 12 months after VNS showed different degrees of improvement as compared with the preoperative one; 15 patients had McHugh grading I-II.Conclusion:The EEG improvement effect of DRE patients after VNS is gradually improved with time; in some patients, the EEG improvement is earlier than improvement of clinical symptoms.
