Recent advance in encephalitis associated with anti-Kelch-like protein 11 antibody
10.3760/cma.j.cn115354-20220301-00108
- VernacularTitle:抗Kelch样蛋白11抗体相关脑炎的研究进展
- Author:
Anqi WANG
1
;
Fangchao JIANG
;
Guozhong LI
;
Di ZHONG
Author Information
1. 哈尔滨医科大学附属第一医院神经内科，哈尔滨 150001
- Keywords:
Kelch-like protein 11;
Encephalitis;
Spermatocytoma
- From:
Chinese Journal of Neuromedicine
2022;21(6):636-641
- CountryChina
- Language:Chinese
-
Abstract:
Anti-kelch-like protein 11 (KLHL11) antibody associated encephalitis is a type of paraneoplastic encephalitis associated with testicular seminoma, with marginal encephalitis symptoms appearing in a few cases. Vertigo, hearing loss, and tinnitus are common and unique clinical symptoms in patients with KLHL11 antibody associated encephalitis. Treatment options include immunotherapy, symptomatic therapy, and antitumor therapy for patients with concomitant tumors. In order to improve the understanding of this disease among clinical medical workers, the authors review the epidemiological characteristics, pathogenesis and clinical manifestations of anti-KLHL11 antibody associated encephalitis as follows.
