Recent advance in quantitative MRI in glymphatic systems of the brain
10.3760/cma.j.cn115354-20211217-00825
- VernacularTitle:脑部类淋巴系统的定量MRI成像研究进展
- Author:
Yali ZHAO
1
;
Hongyu WU
;
Linhan ZHAI
;
Weiqiang LIANG
;
Huan LIU
;
Chengdong PENG
;
Qiuxia WANG
;
Jing ZHANG
Author Information
1. 华中科技大学附属同济医院放射科,武汉 430030
- Keywords:
Glymphatic system;
MRI;
Quantitative technique;
Central nervous system;
Cerebrospinal fluid tracer
- From:
Chinese Journal of Neuromedicine
2022;21(3):316-320
- CountryChina
- Language:Chinese
-
Abstract:
The glymphatic system, as "waste" clearance pathway in the brain, plays a critical role in maintaining the homeostasis of the brain cell microenvironment. It has been found that changes in the glymphatic system are common in many neurological diseases. MRI is currently the only technology that can achieve human glymphatic imaging, and has the advantages of high soft tissue resolution and sensitivity to tracers. Quantitative MRI can objectively evaluate the changes of inflow and outflow of glymphatic system. Therefore, in this review, we introduce the application of quantitative MRI technology in the glymphatic system in detail, aiming to provide help for the diagnosis and treatment of diseases related to glymphatic system.