Recent advance in neuron ferroptosis after intracerebral hemorrhage
10.3760/cma.j.cn115354-20210719-00450
- VernacularTitle:脑出血后神经细胞铁死亡的研究进展
- Author:
Yue CHEN
1
;
Guofeng WU
;
Siying REN
Author Information
1. 贵州医科大学临床医学院,贵阳 550003
- Keywords:
Intracerebral hemorrhage;
Ferroptosis;
Oxidative damage
- From:
Chinese Journal of Neuromedicine
2022;21(1):87-91
- CountryChina
- Language:Chinese
-
Abstract:
Intracerebral hemorrhage (ICH) is an acute cerebrovascular disease with the highest mortality in subtype of stroke, accounting for 15%-20% of all strokes. There was no specific treatment for ICH currently. The mechanism of secondary neurological impairment after ICH remains unclear. Whether it is related to the process of ferroptosis caused by iron deposition is worth to further discuss. This paper reviews the related published articles about ferroptosis, which include mechanisms, inhibition methods and biomarker of ferroptosis.