Recent advance in fatty acid binding protein 7 in central nervous system
10.3760/cma.j.cn115354-20210613-00379
- VernacularTitle:脂肪酸结合蛋白7在中枢神经系统中的研究进展
- Author:
Weiwei HE
1
;
Tingting PENG
;
Chen GOU
;
Xiaoming WANG
Author Information
1. 川北医学院附属医院神经内科，川北医学院神经疾病研究所，南充 637000
- Keywords:
Fatty acid-binding protein 7;
Central nervous system;
Glioma;
Mental disorder;
Brain injury
- From:
Chinese Journal of Neuromedicine
2021;20(12):1287-1292
- CountryChina
- Language:Chinese
-
Abstract:
Fatty acid binding protein 7 (FABP7) is a small molecular cytoplasmic protein. As a cellular fatty acid chaperone, it binds specifically to ligands such as DHA and is widely involved in physiological and pathological processes. During brain development, FABP7 is heavily expressed in neural stem cells, astrocytes and oligodendrocyte precursor cells, which plays a key role in regulating the pathology process of the central nervous system diseases. This article reviews the structure, expression and function of FABP7 and its related research progress in central nervous system disease.
